In management of Guillain-Barré syndrome, what is the initial priority?

• A. Stabilize vital signs and provide supportive care
• B. Move to ICU and monitor ventilatory function
• C. Initiate plasmapheresis immediately
• D. Begin high-dose corticosteroids

Answer: (A)

The first priority in Guillain-Barré syndrome is to stabilize the patient and provide supportive care because weakness can rapidly progress to respiratory failure and autonomic instability. This means securing the airway and ensuring adequate ventilation, continuous monitoring, and hemodynamic support, with readiness for ICU-level care if needed. After stabilization, more specific treatments like plasmapheresis or IVIG can be considered, while high-dose corticosteroids are not beneficial for acute management.